514 pyrazinamide, rifampicin, spectinomycin
pyrazinamide (Isopas, Pyzamed, PZA, Zinamide, Zinastat)
Pyrazinamide is used to treat tuberculosis (TB) (see Chapter 25).
In what forms does this
medicine come?
Tablets: 400 mg
Liquid: 30 mg/ml
Side
effects
How much and
when to take
Who should
not take this
medicine?
The doses for tuberculosis
medicines differ from region to
region. See a health worker. (Take
pyrazinamide in combination with
other drugs, see page 389).
People with liver damage
or hepatitis should not
take this medicine.
Warning
Yellow skin or eyes, rash, fever, loss of
appetite, tiredness, liver tenderness,
gout or ar thritis. If you have any of
these problems, get medical help.
Pregnant and breastfeeding women
should avoid this drug since its effects
on the baby are not known. It is very
important that you take the entire course
of treatment for tuberculosis. If not, you
might infect other people or get sick again
with a kind of TB that is very hard to cure.
rifampicin (Resimin, rifampin, Rifastat)
CAUTION
Rifampicin is an antibiotic used to treat tuberculosis (TB) (see Chapter 25) and other kinds of infections,
including leprosy (Hansen’s Disease).
In what forms does
this medicine come?
Tablets: 150 or 300 mg
Liquid: 20mg/ml and
50 mg per 5 ml
Ampules for injection: 600 mg
How much and
when to take
Doses for tuberculosis
medicines differ from region
to region. See a health worker.
(Take rifampicin in combination
with other drugs, see page 389).
Who should not
take this medicine?
People with liver damage or
liver disease should not take
this medicine.
Side effects
• Nausea, vomiting, loss of appetite,
diarrhea, cramps
• Hot face, itching, rash
• Headaches, fever, chills, bone pain
• Yellow skin or eyes
Except for yellow skin or eyes, these side effects usually
happen 2 to 3 hours after taking this medicine and can
sometimes be avoided by taking the medicine with food.
Information
you should
know
May turn urine, stool, tears, sweat, or
spit a red-orange. It will stain contact
lenses too.Take the entire course of
treatment for tuberculosis. If not, you
can infect others or get sick again with
a kind of TB that is very hard to cure.
Do not take more than 600 mg a day.
spectinomycin (SCM, Stanilo,Togamycin,Trobicin)
Spectinomycin is a strong aminocyclitol antibiotic used to treat most types of gonorrhea, but it does not
work for gonorrhea of the throat. It is especially useful for people allergic to penicillin and cephalosporin
antibiotics.
In what forms does
this medicine
come?
Vials for injection: 2 grams
Side
effects
Chills, pain or redness at
injection site, dizziness, nausea.
How much and
when to take
For gonorrhea or PID: Inject
2g (2000 mg) into muscle one
time only. (See pages 268 and
275 for drug combinations to
treat these problems.)
Other
medicines
that may
work
for gonorrhea: cefixime, ceftriaxone
for PID: azithromycin, cefixime,
ceftriaxone, doxycycline,
metronidazole, tetracycline
Where Women Have No Doctor 2012