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Gene Machine: The Lac Operon
Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.
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Teaching Resources
Main Topics
- Gene Regulation
- Genes
- Cellular Metabolism
- Cells
Sample Learning Goals
- Predict the effects on lactose metabolism when the various genes and DNA control elements are mutated (added or removed).
- Predict the effects on lactose metabolism when the concentration of lactose is changed.
- Explain the roles of LacI, LacZ, and LacY in lactose regulation.
Teaching Ideas
| Title | Authors | Level | Type | Updated |
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Gene Machine: Lac Operon -an inquiry lesson
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Trish Loeblein | UG-Intro | Lab CQs HW |
8/11/12 |
| Study Guide for lac Operon Simulation | Daryle LaFleur | UG-Intro HS |
HW Lab |
6/4/12 |
You can submit your own ideas and activities.
Translated Versions:
| Language | Language (Translated) | Simulation Title | ||
|---|---|---|---|---|
| Afrikaans | Afrikaans | Gene Masjien: Die Lak Operon | Run Now | |
| Arabic, Saudi Arabia | العربية (السعودية) | مصنعة الجينات: اللاك أوبريون | Run Now | |
| Basque | Basque | Geneen Makina: Lac Operona | Run Now | |
| Brazilian Portuguese | português (Brasil) | Gene Machine: The Lac Operon | Run Now | |
| Chinese - Simplified | 中文 (中国) | 基因合成机：乳糖操纵子 | Run Now | |
| Chinese - Traditional | 中文 (台灣) | Gene Machine: The Lac Operon 基因機器: 乳糖操縱組 | Run Now | |
| Danish | Dansk | Genmaskine: Laktosegengruppe | Run Now | |
| Estonian | Eesti | Geenimasin: lac operon | Run Now | |
| French | français | La machine à gène : Le lac Operon | Run Now | |
| German | Deutsch | Genmaschine: Das Lactose-Operon | Run Now | |
| Greek | Ελληνικά | Μηχανή γονιδιών: The Lac Operon | Run Now | |
| Hebrew | עברית | מכונת הגנים: אופרון הלקטוז | Run Now | |
| Hungarian | magyar | Géngép: a lac-operon | Run Now | |
| Italian | italiano | Macchina del Gene: L'Operone del Lattosio | Run Now | |
| Japanese | 日本語 | 遺伝子装置 : ラクトースオペロン | Run Now | |
| Korean | 한국어 | 유전자 기계: 락 오페론 | Run Now | |
| Macedonian | македонски | РЕГУЛАЦИЈА НА ЛАКТОЗА - ГЕНСКИ МАШИНИ Gene Machine: The Lac Operon | Run Now | |
| Persian | Persian | ماشين ژن:لاکتوز اپرون | Run Now | |
| Polish | polski | Fabryka genów: Operon Laktozowy | Run Now | |
| Serbian | Српски | РЕГУЛАЦИЈА ЛАКТОЗЕ- ГЕНСКЕ МАШИНЕ Gene Machine: The Lac Operon | Run Now | |
| Spanish | español | La Máquina de Genes: El Operón Lac | Run Now | |
| Spanish (Peru) | español (Perú) | Máquina Génica: El Operon Lac | Run Now | |
| Turkmen | Turkmen | Genetiki maşyn: laktuloza operon | Run Now |
Software Requirements
| Windows | Macintosh | Linux |
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Microsoft Windows
XP/Vista/7 Sun Java 1.5.0_15 or later |
OS 10.5 or later
Sun Java 1.5.0_19 or later |
Sun Java 1.5.0_15 or later |
Credits
| Design Team | Third-party Libraries | Thanks To |
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