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Pellagra

Contents of this page:

Illustrations

Vitamin B3 deficit
Vitamin B3 deficit

Alternative Names    Return to top

Vitamin B3 deficiency; Deficiency - niacin

Definition    Return to top

Pellagra is a disease that occurs when a person does not get enough niacin (one of the B complex vitamins) or tryptophan (an amino acid).

Causes    Return to top

Pellagra is caused by having too little niacin or tryptophan in the diet. It can also occur if the body fails to absorb these nutrients. It may develop after gastrointestinal diseases or with alcoholism.

The disease is common in parts of the world where people have a lot of corn in their diet.

Symptoms    Return to top

Symptoms of pellagra include:

References    Return to top

Brust JCM. Nutrition- and alcohol-related neurologic disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 443.

Chenoweth WL. Vitamin B complex deficiency and excess. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th Ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 46.

Update Date: 11/16/2008

Updated by: Linda Vorvick, MD, Family Physician, Seattle Site Coordinator, Lecturer, Pathophysiology, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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