A heart positron emission tomography (PET) scan is an imaging test that uses a radioactive substance (called a tracer) to look for disease or poor blood flow in the heart.

Magnetic resonance imaging (MRI) and computed tomography (CT) scans reveal the structure of the heart. A PET scan can tell your doctor whether areas of your heart muscle are receiving enough blood flow. It also can tell your doctor whether areas of your heart are healthy or contain scar tissue.

The health care provider will inject a small amount of a radioactive material into one of your veins, usually on the inside of the elbow. The substance travels through the blood and collects in the tissues of the heart.

You will be asked to wait nearby as the radioactive substance is absorbed by your body. This usually takes about 1 hour.

Then, you will lie down on a table that slides into a tunnel-shaped hole in the center of the PET scanner. Electrodes for an electrocardiogram (ECG) will be placed on your chest.

The PET machine detects energy given off by the radioactive substance and changes it into 3-dimensional pictures. The images are sent to a computer, where they are displayed on a monitor for the health care provider to read.

You must lie still during the PET scan so that the machine can produce clear images of your heart.

The test takes about 90 minutes.

You must sign a consent form before having this test. You will be told not to eat anything for 4 - 6 hours before the PET scan, although you will be able to drink water.

Tell your doctor if you are pregnant or think you might be pregnant.

Also tell your doctor about any prescription and over-the-counter medicines that you are taking, because they may interfere with the test.

People who take insulin injections for diabetes may also need special preparation. If you use insulin, call the PET scan office the day before the study for instructions.

Be sure to mention if you have any allergies, or if you’ve had any recent imaging studies using injected dye (contrast).

During the test, you may need to wear a hospital gown. Take off any jewelry, dentures, and other metal objects because they could affect the scan results.

You will feel a sharp prick when the needle with the radioactive substance is inserted into your vein. You shouldn’t feel anything during the actual PET scan.

A PET scan can reveal the size, shape, position, and some function of the heart, so your doctor can make sure it is working as well as it should.

It is most often used when other tests, such as echocardiogram (ECG) and cardiac stress tests do not provide enough information.

This test can be used to diagnose heart problems and show areas in which there is poor blood flow to the heart.

Several PET scans may be taken to determine how well you’re responding to treatment for heart disease.

There are no problems detected in the size, shape, or function of the heart. There are no areas in which the radiotracer has abnormally collected.

Abnormal results may be due to:

• Coronary artery disease
• Heart failure or cardiomyopathy

The amount of radiation used in a PET scan is low. It is about the same amount of radiation as in most CT scans. Also, the radiation doesn’t last for very long in your body.

However, women who are pregnant or are breastfeeding should let their doctor know before having this test. Infants and fetuses are more sensitive to the effects of radiation because their organs are still growing.

Before receving the contrast, tell your health care provider if you take the diabetes medication metformin (Glucophage) because you may need to take extra precautions.

It is possible, although very unlikely, to have an allergic reaction to the radioactive tracer. Let your doctor know if you have ever had an allergic reaction to injected contrast dye. Some people have pain, redness, or swelling at the injection site.

It is possible to have false results on a PET scan. Blood sugar or insulin levels may affect the test results in people with diabetes.

Most PET scans are now performed along with a CT scan. This combination scan is called a PET/CT.

Udelson JE, Dilsizian V, Bonow RO. Nuclear cardiology. In: Libby P, Bonow RO, Mann DL, Zipes DP. Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 16.