isoniazid, ketoconazole 505
isoniazid (Bisonid, INH, Isoniazdum, isonicotinic acid hydrazide, Odinah, Zidrid)
Isoniazid is used to treat tuberculosis (TB) in combination with other medicines. See Chapter 25.
People with HIV can use isoniazid to prevent latent TB (TB with no signs) from becoming active TB.
In what forms
does this
medicine come?
How much and
when to take
Who
should not
take this
medicine?
Tablet: 100 or 300 mg
Syrup: 50 mg per 5ml
The doses for medicines to
treat tuberculosis differ from
region to region. See a health
worker. (Take isoniazid in
combination with other drugs, see
page 389.)
For prevention of TB in adults
with HIV: take 300 mg by mouth
every day for 6 months to
3 years.
Anyone who has hepatitis,
liver disease, or has taken
isoniazid before and had
liver problems, should not
take this drug.
Side
effects
May cause pain or numbness in arms
and legs. Sometimes isoniazid may cause
severe hepatitis with signs like tiredness,
loss of appetite, nausea, vomiting, dark
urine, or yellowing of eyes. If this happens,
stop taking this medicine immediately.
Information
you should
know
Signs of taking
too much
Never take more than 300 mg
a day if you take it every day,
or 900 mg if you take it 3 times
a week. It is important to take
the full course of treatment for
tuberculosis. If not, you can infect
other people or get sick again
with a kind of TB that is very hard
to cure.
Nausea, vomiting, dizziness, slurred
speech, blurred vision. If you take
too much, take one g or more of
pyridoxine (vitamin B6).
ketoconazole (Nizoral)
Ketoconazole is a strong anti-fungus medicine that is used to treat thrush and other yeast infections. Use
only if you have HIV and other remedies do not work.
In what forms
does this medicine
come?
Tablets: 200 mg
Also comes as
2% skin cream
and 1% shampoo
How much
and when
to take
For fungal infection
on the skin: Take
200 mg by mouth
once a day for
10 days.
For yeast infection inside the mouth (thrush):
Take 200 mg by mouth 2 times a day for 14 days.
Warning
Information
you should
know
Do not take if you are pregnant
or breastfeeding. Do not put
cream or shampoo in vagina.
Take with food. If taken by
mouth, it may give you hot
flashes if you also drink alcohol.
This medicine works best if
taken with orange juice or
another citrus fruit.
Side
effects
May cause nausea, vomiting.
Other medicines
that may work
for yeast infections without
STIs: clotrimazole, fluconazole,
gentian violet, miconazole,
nystatin, vinegar
Where Women Have No Doctor 2012